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Symbol
Name
ID

Ndrg1
N-myc downstream regulated gene 1
MGI:1341799

Phenotype annotations related to nervous system

Darker colors indicate more annotations

Human Phenotypes

Abnormality of visual evoked potentials

Frequent falls

Onion bulb formation

Segmental peripheral demyelination/remyelination

Demyelinating peripheral neuropathy

Axonal loss

Postural tremor

Abnormal auditory evoked potentials

Decreased motor nerve conduction velocity

Decreased nerve conduction velocity

Decreased amplitude of sensory action potentials

Areflexia

Hyporeflexia

Gait disturbance

Inability to walk

Unsteady gait

Motor delay

Somatic sensory dysfunction

Impaired distal tactile sensation

Distal sensory impairment

Impaired distal proprioception

Impaired distal vibration sensation

Disease(s) Associated with NDRG1

Charcot-Marie-Tooth disease type 4D

Mouse Phenotypes		abnormal axon morphology	decreased myelin sheath thickness	abnormal sciatic nerve morphology	peripheral nervous system degeneration	demyelination	abnormal action potential	decreased nerve conduction velocity	decreased prepulse inhibition
Availability	Mouse Genotype	abnormal axon morphology	decreased myelin sheath thickness	abnormal sciatic nerve morphology	peripheral nervous system degeneration	demyelination	abnormal action potential	decreased nerve conduction velocity	decreased prepulse inhibition
	Ndrg1^em1Lxli/Ndrg1^em1Lxli
	Ndrg1^str/Ndrg1^str
	Ndrg1^tm1Myta/Ndrg1^tm1Myta
	Ndrg1^{tm2b(KOMP)Wtsi}/Ndrg1^{tm2b(KOMP)Wtsi}

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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